The melting pot, known as the US, is more melted together than we thought. But geneticists are finding surprising patterns.
In the United States, almost no one can trace their ancestry back to just one place. And for many, the past may hold some surprises, according to a new study. Researchers have found that a significant percentage of African-Americans, European Americans, and Latinos carry ancestry from outside their self-identified ethnicity. The average African-American genome, for example, is nearly a quarter European, and almost 4% of European Americans carry African ancestry.
I have tested at 23andMe partly to prove kindship to a potential maternal relative I found and partly to know my ancestry, and yes, my "spit test" is used for research. I found that my ancestry composition pretty closely followed the paper trail I had built for my maternal side, and I was able to determine most of my paternal heritage partly from what didn't match my maternal paper trail and mostly because I had a close match to someone (at 26% shared DNA) that was not on my maternal side, but that person hasn't be able to accept that DNA doesn't lie).
But, I digress. One of the things this study found was genetic patterns in the 3 largest ethnic groups were different depending on which state a family lived.
The new study adds an unprecedented level of detail to patterns that had been noticed in previous, more general studies. For example, the 23andMe data reveals that the proportion of different ancestries, even within one self-identified ethnic group, vary significantly by state. Latinos with the highest proportion of African ancestry (about 20%) are from Louisiana, followed by states such as Georgia, North Carolina, New York, and Pennsylvania. In Tennessee and Kentucky, Latinos tend to have high proportions of European ancestry. And in the Southwest, where states share a border with Mexico, Latinos tend to have higher proportions of Native American ancestry.
A lot of a states history can be found in ones genetic ancestry. But, the bottom line is racial lines are getting blurred, irregardless of ones self described ethnicity. While this is truly a great melting pot, one problem we will see is that doctors will have no choice but to consider the whole person in their genetic glory and not ethnic categories.
Do go check out the full study, it really is fascinating.
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...
'Irregardless!' Arrrgh......
Before this thread gets
Before this thread gets hijacked by the grammar police, I'd like to say that I appreciate these distinctions among Latinos. As a semi-Latina (my mom is Puerto Rican), I know first hand that it's silly to lump them (us) all together, genetically or even culturally. Latino/Hispanic is not a race or even an ethnicity. About the only single common trait you can bank on is linguistic commonality.
And, somewhat interestingly, Puerto Ricans and Mexicans don't much care for Cubans, who have long occupied a unique and favored niche in America del Norte.
As I recall
(in reply to Bbeanster)
Betty, as I recall when I lived in NY city, Puerto Rican's didn't much care for Mexicans, either. But that was several decades ago.
I think this study, particularly as it expands with more people testing, has the potential to be used for a number of national issues, particularly in immigration and medical issues.
When I dipped my toe into genetics I truly did not expect to be so consumed. There are basics I was taught in high school science, that are really overly simplistic.
Race?
Race is a social construct.
Ethnicity not so much.
~m.
Ethnicity vs. Race
(in reply to Michael)
Ethnicity vs. Race
Social Construct
(in reply to Stan G)
AAA Statement on Race
I Fail to Understand ...
(in reply to Stick)
why this was directed at me or what it has to do with the discussion. Genetic genealogy, finding ones roots, has become popular as the cost of genetic testing has come down. The three major companies only report results relating to one's ancestry; although, 23andMe, I understand, continues to test for possible medical issues but are currently not permitted to report them because of a ruling by the FDA.
Relax
(in reply to Stan G)
It was a contribution to a conversation. Although they hedged their bets, the link you provided gives the appearance that 'race' is a real biological concept. I thought the AAA statement might help clarify things. Race is a social construct.
Bullworth
Bullworth was right.
+1 The movie was kinda bad on
(in reply to Holler-Dweller)
+1
The movie was kinda bad on some levels, but the quote you are probably referring to is classic.
"Everybody just needs to keep f***ing everybody until we're all the same color."
Or something like that.
Now that I've got all my
Now that I've got all my Christmas stuff packed off to Cali and I can breathe a minute, I'd like to amend my earlier post. Not all latino/hispanics share a common language. Spanish is a second language for many of the the indigenous people of Central America, who have their own languages and cultures.
There was a lot of variety in my mother's family – everything from fair skinned redheads and blonds to folks with distinctly African features. Puerto Rico really is a melting pot.
What would you call
(in reply to Bbeanster)
What would you call Brazilians?
I guess Brazilians have never
(in reply to WhitesCreek)
I guess Brazilians have never migrated to this country in numbers sufficient to have "earned" an ethnic label, so I don't know what the heck they'd be called. Portuguese is so similar to Spanish (even more so than Italian) that there's really not that much difference, linguistically. But although I took South American history in college, I really don't remember much about anything between the conquistadores and Simon Bolivar, and even less about Brazil, sad to say.
It's an interesting question.
Portugese
(in reply to Bbeanster)
Brazilians didn't mind so much my poor Spanish, but in Lisbon they detested Spanish and took offense at Brazillian Portuguese!!! Bon dia - not Bom jia!
Multiple DNAs?
DNA is apparently more complicated than one person, one set of DNA. "it’s quite common for an individual to have multiple genomes." See: (link...).
-- OneTahiti
Chimera
(in reply to onetahiti)
There's been a few cases of human chimera's, I believe the most recent (in the news) case was a woman that was originally tested and showed she wasn't her children's mother. DNA tests from a cervical smear showed she carried two sets of DNA.
DNA Testing
It’s an interesting article although statistically it is somewhat beyond my comprehension. I’m somewhat surprised to note the two states where the self-reported Latinos have the largest percentage of European ancestry are Tennessee and Kentucky.
Like CE, I have gotten deeper into genetic genealogy than I intended. For those who might be interested, my free advice for what it’s worth is to test with 23andMe first even though it might be slightly more expensive. You’ll get the biggest bang for your buck. Then, if you choose to delve more deeply into your direct parental lines you can test with Family Tree DNA.
I started with Family Tree DNA because I was mainly interested in my maternal grandfather’s ancestry. When I searched on his surname, it appeared several males had been tested. As it turned out, they, like me, had the surname listed as an ancestral surname but were not in the direct male line. I paid extra to have my mother’s ancestry tested which has generated almost 5,000 possible matches making it virtually useless.
Stan, we will need to get
(in reply to Stan G)
Stan, we will need to get together on the genetic genealogy. I tested at 23andme first, and then did the Family Finder at FTdna (Family Tree). I have yet to do the test at ancestry. The mtDNA is often useless, however the YDNA (for males only) can be quite interesting I hear.
For adoptees that are searching for birth family (and are either from closed adoption states and/or have hit a proverbial brick wall), it's suggested to test at ancestry first, then transfer your raw data to FTdna, then test at 23andme. Also upload your raw data to GEDmatch (free site). Each company has it's strengths and weaknesses when it comes to their tools, but ftdna and 23andme both have chromosome browsers that ancestry doesn't.
While everyone has a different experience, I've had the most success finding family members at 23andme. (Their messaging and genome sharing is very cumbersome though.) I've also found their ancestry composition to closely follow my paper-trail at 23andme, whereas FTdna left off my British/Irish connections and doubled the amount of Ashkenazi. However, connections to "matches" will be dependent on the pool of other testers.
Ancestry composition can change, depending on the number of close family members yhat are tested, and 23andme is now working on child phasing (still brushing up on what that means plus how it will/will not change results). The admixture tools over at GEDmatch are fun to play with, but aren't exact (keyword is FUN). If you are predominately European, you'd want to work with the K12 and K15 (both with Oracle) to get your breakdowns.
Blurred lines, sharp sight?
Wonkish but... the evolutionary psychology question on race - whether the human mind has an architecture that disposes humans to notice race - is fascinating. For a comparatively long time humans and their precursors most likely didn't encounter people of divergently different colors. So why do we notice it along with sex and age?
Sciency paper
We're all basically mongrels.
We're all basically mongrels. I keep wanting to check that box on various form, but nobody ever gives me the option.
Proverbial Apples and Oranges
I don't pretend to be an authority; however, race in the context of this conversation refers to observable physical differences that can be traced to observable genetic mutations. How individuals relate to those differences in another matter.
I did find the statement interesting but, IMO, unrelated to the conversation.
Or...
(in reply to Stan G)
You could read what "authorities" on the subject have to say?
Bottom Line
We're all Homo Sapiens.
Exactly. By treating race as
(in reply to Stan G)
Exactly. By treating race as though it were a real, meaningful concept we make a small contribution to the continuation of a social construct with real-world effects.
Memories
This conversation brings back memories of a class we were required to take in college. A general course combining biology, psychology and sociology intended to introduce us to fields outside our chosen major. Seldom did one professor get to finish his lecture before the other two began arguing with him.
I am mildly amused by the use
I am mildly amused by the use of "African" to describe ancestry. It is even less specific than "Latino". From the Mediterranean Ocean to the Congo to the most Southern parts there are such variations in skin color and features as to be opposites if that concept had any application. From Pygmies to Masai, Moroccans to Rawandans to Afrikkkans it is a geographically huge and extremely biologically diverse continent. Language, religion, lifestyle, and Gawd only knows what all are as diverse there as can be.
But it sure is easy to pretend that describing something or someone as "African" actually told you something of import. (Just think, Charlize Theron is an "African-American.)
In Case You Missed It
(in reply to cafkia)
Black vs. African-American
"Black" is a self-descriptor.
(in reply to Stan G)
"Black" is a self-descriptor. It was adopted in the '60s as a response to the long time attitude in the community that lighter skin and straighter hair were preferred but that the gradient effect was acknowledged. Lighter was better and darker was worse. When we called ourselves "Blacks" we denied all of that. It was a way of refusing to give others power over us. There was never any actual requirement of genetics or appearance to use the term as there has never been any authority capable of dictating such.
"African-American" is a well-intentioned effort to do the things that "Black" was meant to do as well as honor our history. Unfortunately, as I mentioned above, it is so vague and non-specific about anything as to be essentially meaningless.
This is why I have always rejected descriptions of Obama as "half-Black". To me that seems an incredibly stupid thing to say or think. "Black" is a choice, you're Black if you say you are.
Eventually, I might take a look at that link and see what they have to say about it but, as I lived it, I'll probably stick with my understanding.
In Brief,
(in reply to cafkia)
Her focus is on how one is perceived when identified as either African-American vs. Black.
I've known your thoughts for several years now; but, even though you find Black acceptable, I still have a problem referring to a person as black. It may go back to the day our sixth grade teacher shocked us out of our seats with a book slammed against the desk. She had overheard someone refer to another as colored and let us know in no uncertain terms why we were never to do so.
Homo sapiens of different skin colors are not different races
Or Homo sapiens of different earlobe attachments, tongue twirling capabilities, presence/absence of widow's peaks or ___________ phenotypes aren't different races either.
Beyond simple tolerance it'll take peoples' deeper understanding of evolutionary biology to begin ridding ourselves of racism. Nina Jablonski does a great job in her enthralling-for-the-genre book, Skin: A Natural History moving us in that direction. I had some high school students in a human evolution unit engaged by this brief segment below. Her paper the Evolution of Human Skin and Skin Color is here.
Interesting Video
(in reply to Mike Knapp)
I cringe to think a student can graduate from high school without understanding that we have all evolved from common African ancestors.
One of the few times I have held my tongue was when a distant cousin, a retired Indiana schoolteacher, suggested we meet in Cincinnati so we could visit the Creation Museum. In her opinion, it is wonderful and everyone should visit it.
One of the reasons
One of the reasons I found this article so interesting, is that I have been working with a distant cousin to find where we fit. One the testing sites, we are projected to be 5th to distant cousins, and at this point, our most recent common ancestor (MRCA) would be around my 5th or 6th great grandfather. Apparently, GGGGGG granddad help to add to that European mixture.
Without giving all our personal information, I show to be 97-99% European. This distant cousin is about 65% African (west African) 30% European and a smattering of American Indian. (Cafkia, the mtdna shows the exact areas in Africa this cousin descended from, but I choose to keep most of that information private in this discussion)
Because of the way this distant cousin appears, one would say we could not be related, and I'm sure when filling out forms they would check the little box for "African-American" and the dna for this cousin tells a far different story.
One of the things we find, is that when the US was settled by/invaded by Europeans, diluting the DNA of inhabitants is an aggressive act of dominance. (Now I'm late, will try to finish my thoughts later)
No question
(in reply to CE Petro)
This stuff is fascinating. Really appreciate your posting it C.E.. Speaking of domination, the science right now seems to point to a potentially similar finding wrt Homo sapiens' interaction with Neanderthals in Europe. The thinking about the disappearance of the Neanderthals was once bound to the notion that H.sapiens simply out-competed H.neanderthalis. But now, ever since the great, precise and time-consuming genetic work by S. Pääbo at the Max Planck Inst. for Evolutionary Anthropology, Dept. Evolutionary Genetics, it looks like that earlier picture is morphing into one which suggests that H.neanderthalis was simply hybridized into extinction aka the "assimilation model". The last link is a neat and short talk by Richard Green of UC Santa Cruz on the topic.
Neanderthal DNA
(in reply to Mike Knapp)
Mike, I'll probably read those when I'm sitting at the hospital awaiting a grandchild tonight, and comment after I read them.
But, because you mentioned Neanderthals, I thought I'd mention that we all have some amount of Neanderthal DNA. Which would lend itself to the support the hybridization theory, don't you think?
Yes
(in reply to CE Petro)
The presence of H.neanderthalis DNA in the human genome could indicate other things but it is a good piece of evidence that they were hybridized out of existence. Perhaps you had time to read some.
Congrats on the grandbaby! Hope everyone is well.
See John Hawks
(in reply to metulj)
180 million Neanderthals
Denisovans
(in reply to Mike Knapp)
Cousins On The Hominid Tree
CE
Given that we at one time shared common ancestors, I took issue with Micheal and Stick because they appear to ignore your referenced article and the advances made in DNA analysis during the past fifteen years. For $99.00 and a vial of saliva your race and/or racial mixture can be identified. For a few hundred, they can determine your ancestors migration routes.
I've only tested with FamilyTreeDNA and question the results. The percentages of Scandinavian and Southern European ancestry it reports is much higher than my paper trail would indicate. I plan to test with 23andMe next month. I'm not particularly interested in finding cousins;
but, I do respond if someone thinks there might be a connection.
Except it doesn't tell you
(in reply to Stan G)
Except it doesn't tell you jack about your "race". It tells you the broad geographic areas where your ancestors came from... Now do you see the difference? Or, are you just being obtuse?
More here
Which is Why I Question My Family Finder Results
(in reply to metulj)
I have no known Scandinavian or Southern European ancestors. FamilyTreeDNA, however, indicates I have approximately 10% of each within the last five or so generations.
Thanks to others, I have rather extensive paper trails.
From the Summary
(in reply to Stick)
What leads you to believe the study included place of origin?
Key word: identities. If you
(in reply to Stan G)
Key word: identities. If you follow the link I provided you it details how 23andme works and how it can be problematic. As metulji notes above, the concept has staying power in our language (even among those who should know better, including a lot of psychologists) but no biological basis. That is all that I'm trying to point out.
Ancestry Compositions
(in reply to Stan G)
Stan, none of the ancestry compositions are 100% accurate, but they are fun to play with. What I have learned is that the predictions at each company are based on comparing your genome with the other testers at that company. It is also my understanding that when you test close relatives your ancestry composition would/could change with the new information.
Taking that into consideration, at 23andme I had also tested a fairly close relative (my maternal grandmother is this person's mother) so my ancestry composition would be more accurate. Because I tested after 23andme changed their chip, I wasn't able to transfer that data to FTdna.
CE
Congratulations on the anticipated arrival on your holiday blessing.
I do expect 23andme to generate a different ancestral history since their autosomal database, I understand, is approximately 4X the size of the FTDNA database and it generates a more detailed report. That's why I suggested earlier that those with an interest test with 23andme first.
I'm testing out of curiosity rather than genealogy. Not particularly looking for new cousins. Glad to get rid of one who sent daily ultra-conservative emails, although I was not happy to hear of his failing health since he maintained a family webpage long out of date.
Don't particularly like to use KV for personal exchanges. Will connect after your life settles down. Would like to know more about your finding particularly if you have New York roots.
Perhaps a suggested wrap to this thread
could be the great work done at PBS in their series "Becoming Human" and an excellent PBS piece on Neanderthals, note the discussion with John Hawks in the last 15 minutes; all links at youtube in HD. each right at ~52min.
Becoming Human Pt 1
Becoming Human Pt 2
Becoming Human Pt 3
Decoding Neanderthals
Interesting discussion, interesting personal experience
A few years ago I was found to be the best 'match' for a stem cell transplant for a man with leukemia. This was a pretty big deal (on many levels). He and I had to match on at least 7 (10 is best) of our HLA (human leukocyte antigens) to give him the best chance for survival. I don't know exactly how many we matched on but I understand that we are a better DNA genetic match than I am with either my mother or father or even my child. Maybe even a better match than my siblings. I was a better match than any of his immediate family too, apparently, since he was looking on the NMDP registry for a donor.
As an aside, after my stem cells were transplanted into him, if everything worked the way it was supposed to, my cells engrafted within about 30 days. This means they started growing new, healthy stem cells in his bone marrow. He had already had his immune system destroyed with chemo about the same time (3-5 days before the transplant) that I began taking medication to make my bones create copious amounts of stem cells, so my cells were literally a 're-boot' of his immune system. After the transplant his blood type changed to mine and he was now a chimera: one set of DNA for his blood (mine) and his own DNA.
This was/is still pretty mind-blowing for me, but what's even more interesting is that he was an "international" donation. Unfortunately, for my curiousity's sake I don't have any way of even knowing what country he's from, much less how he fared from the transplant. The international rules allow the recipient's treatment center to set the terms of whether any info or contact can ever be established and his allows no info ever. In the US recipient and donor can agree (must be mutual) to have info/contact info shared after one year. Other countries say three years, five years. His center said nothing exchanged, ever. I was disappointed to be sure, but I'm so incredibly grateful to have been allowed such an awesome life experience as this.
Anyway, I'm writing all this not to self-congratulate. I wanted to join the discussion to share my personal experience with the mystery of genetics and DNA. Incidently, I do have an insatiable curiousity and, after a little googling, I found just a very few treatment centers that allow no contact ever between donor and recipient. I believe that it must be in England (I have no reason to believe there was any ancestral connection to the other countries) and my maternal grandfather was from England. Maybe some distant cousin? It's all been so very cool to think about.
About 13 years ago my
(in reply to SouthHeaven)
About 13 years ago my friends' 7-year-old son was diagnosed with leukemia. They eventually found a match for him with a scientist who was doing stem cell research with cord cells in Belguim. This was when Bush had mad stem cell research illegal in the United States. Needless to say my friends became advocates for stem cell research. Now in Arkansas there is a cord bank and doctors are required to discuss it with pregnant women.
And that young boy has grown up to be a brilliant college student who is interested in going to law school.
Service
Was your dad stationed abroad during military service?
Latest on sapiens neanderthal inbreeding
Ewen Callaway Nature News 13 May 2015
Early European may have had Neanderthal great-great-grandparent
Outstanding PBS series on First Peoples Tonight
2nd of 3 part series airs tonight at 9pm on PBS. First one was absolutely superb.
First Peoples
Denisovans
(in reply to Mike Knapp)
(This is CE -- not on my 'puter, so posting anonymously)
I was reading about the Denisovans just the other day. Pretty fascinating. I'll try to pull that article up and share the link.
I know how much (approximate) Neanderthal dna I have in my genome, I think it would also be interesting to see just how much of my genome is Denisovan. I believe there was discussion of that article on the ISOGG (International Society of Genetic Genealogists) facebook page.
Denisovans Article
(in reply to CE2)
So, it turns out the article I was reading on the Denisovans was originally published in Live Science in December of 2013. So info is not as new as I thought. But, it's still interesting.
If you have your raw atdna data uploaded to Gedmatch, they do have a tool to check against "archaic dna", so I checked my kit once again. I do share a few very small segments with "Denisova, Siberia," but this one is a different subject.

Thanks for the heads up! Good
(in reply to Mike Knapp)
Thanks for the heads up! Good stuff... and timely.